Diffusion-Based Reconstruction of Antibody CDR Loops using a Structure-Aware Joint Embedding Predictive Architecture
Silico Biosciences
company
Verified
AI & ML interests
Protein Design
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Silico Biosciences
Where AI meets scalable, reliable drug development.
Silico Biosciences is an AI-driven biotech organization focused on accelerating drug discovery using advanced computational models. We develop protein language models that generate and optimize antibody sequences, aiming to turn in silico approaches into life-saving therapeutic molecules. Our flagship project, 🦋 peleke-1, is a suite of targeted antibody sequence generation models.
- Field: AI-guided drug discovery
- Focus: Protein language models & antibody design
- Core goal: Generate therapeutically relevant biological sequences
models 8
silicobio/kukulu
Mask Generation • Updated
silicobio/hoike
Updated
silicobio/peleke-llama-3.1-8b-instruct
Text Generation • Updated • 10
silicobio/peleke-phi-4-merged
Text Generation • 15B • Updated
silicobio/peleke-llama-3.1-8b-instruct-merged
Text Generation • 8B • Updated • 8
silicobio/peleke-phi-4-gguf
Text Generation • 15B • Updated • 10
silicobio/peleke-phi-4
Text Generation • Updated • 10 • 1
silicobio/peleke-mistral-7b-instruct-v0.2
Text Generation • Updated • 17
datasets 4
silicobio/kukulu_prepared_antibody-antigen_structures
Updated • 18
silicobio/hoike_condition_expression_TCGA_various_log2tpmplus1
Updated • 7
silicobio/hoike_normal_expression_GTEx_Analysis_v10_log2tpmplus1
Viewer • Updated • 19.6k • 11
silicobio/peleke_antibody-antigen_sabdab
Viewer • Updated • 9.52k • 81